Pfizer Says Pill Works Well Against Omicron Variant
2021-12-15
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1American drug maker Pfizer said Tuesday that its experimental pill to treat COVID-19 appears to work well against the fast-spreading Omicron variant.
2The company said its study of 2,250 people found the drug reduced hospitalizations and deaths by nearly 90 percent among high-risk adults.
3The full results came from those who took the pill within three to five days of showing COVID-19 symptoms.
4In laboratory testing, Pfizer said the drug also produced good results against the Omicron variant.
5Pfizer tested the antiviral pill against a man-made version of an important protein that Omicron uses to reproduce itself.
6The U.S. Food and Drug Administration is expected to decide soon whether to approve Pfizer's pill and another one from Merck for treatment.
7After strong early results, Merck said last month that its pill only reduced hospitalizations and deaths by 30 percent.
8Currently approved treatments require injections from healthcare professionals.
9But a pill can be taken at home and is easier to send around the world.
10Pfizer said it is also testing its pill among healthier adults, including some who are vaccinated.
11Partial results showed the pill did not reduce symptoms of COVID-19 for four days during or after treatment.
12However, the company said the pill did reduce hospitalizations among healthy but unvaccinated adults by about 70 percent.
13A group of independent medical experts reviewed the data and advised Pfizer to continue the study to get the full results.
14Rochelle Walensky is the director of the U.S. Centers for Disease Control and Prevention.
15She told an NBC television news program that the best protection against COVID-19 is still vaccination followed by an additional shot called a booster.
16In the United States, nearly 800,000 Americans have died during the COVID-19 pandemic.
17The latest increase in deaths came from the Delta variant.
18But the Omicron variant is spreading quickly in parts of the U.S. and around the world.
19Omicron was first identified in South Africa and neighboring Botswana in November.
20The variant has now caused 90 percent of new infections in South Africa.
21On Tuesday, the South African Medical Research Council and Discovery Health,
22a health insurance company, released their study of the Pfizer-BioNTech COVID-19 vaccine defense against Omicron.
23The study showed people who received two shots of the Pfizer-BioNTech vaccine appeared to have just 33 percent protection against infection,
24compared to those who were unvaccinated.
25The vaccine appeared to have much higher protection, about 80 percent, against infections from earlier variants like Delta.
26However, the shots provided up to 70 percent protection against hospitalization.
27The study did not look at those with booster shots since they are not widely available in South Africa.
28The study was based on examining more than 211,000 COVID-19 test results from Sept. 1 to Dec. 7 - a time of increasing Omicron infections in South Africa.
29Dr. Michael Head is a Senior Research Fellow in Global Health at the University of Southampton.
30He urged people not to give the study too much importance since it only covered a short period.
31He told the Associated Press that international scientists are still studying Omicron and officials will need to consider that in decision-making.
32I'm Dan Friedell.
1American drug maker Pfizer said Tuesday that its experimental pill to treat COVID-19 appears to work well against the fast-spreading Omicron variant. 2The company said its study of 2,250 people found the drug reduced hospitalizations and deaths by nearly 90 percent among high-risk adults. The full results came from those who took the pill within three to five days of showing COVID-19 symptoms. 3In laboratory testing, Pfizer said the drug also produced good results against the Omicron variant. Pfizer tested the antiviral pill against a man-made version of an important protein that Omicron uses to reproduce itself. 4The U.S. Food and Drug Administration is expected to decide soon whether to approve Pfizer's pill and another one from Merck for treatment. After strong early results, Merck said last month that its pill only reduced hospitalizations and deaths by 30 percent. 5Currently approved treatments require injections from healthcare professionals. But a pill can be taken at home and is easier to send around the world. 6Testing among lower-risk adults 7Pfizer said it is also testing its pill among healthier adults, including some who are vaccinated. 8Partial results showed the pill did not reduce symptoms of COVID-19 for four days during or after treatment. However, the company said the pill did reduce hospitalizations among healthy but unvaccinated adults by about 70 percent. A group of independent medical experts reviewed the data and advised Pfizer to continue the study to get the full results. 9Rochelle Walensky is the director of the U.S. Centers for Disease Control and Prevention. She told an NBC television news program that the best protection against COVID-19 is still vaccination followed by an additional shot called a booster. 10Vaccine against Omicron 11In the United States, nearly 800,000 Americans have died during the COVID-19 pandemic. The latest increase in deaths came from the Delta variant. But the Omicron variant is spreading quickly in parts of the U.S. and around the world. 12Omicron was first identified in South Africa and neighboring Botswana in November. The variant has now caused 90 percent of new infections in South Africa. 13On Tuesday, the South African Medical Research Council and Discovery Health, a health insurance company, released their study of the Pfizer-BioNTech COVID-19 vaccine defense against Omicron. 14The study showed people who received two shots of the Pfizer-BioNTech vaccine appeared to have just 33 percent protection against infection, compared to those who were unvaccinated. The vaccine appeared to have much higher protection, about 80 percent, against infections from earlier variants like Delta. 15However, the shots provided up to 70 percent protection against hospitalization. The study did not look at those with booster shots since they are not widely available in South Africa. 16The study was based on examining more than 211,000 COVID-19 test results from Sept. 1 to Dec. 7 - a time of increasing Omicron infections in South Africa. 17Dr. Michael Head is a Senior Research Fellow in Global Health at the University of Southampton. He urged people not to give the study too much importance since it only covered a short period. 18He told the Associated Press that international scientists are still studying Omicron and officials will need to consider that in decision-making. 19I'm Dan Friedell. 20Dan Friedell adapted this story for Learning English based on reporting by the Associated Press. Hai Do was the editor. 21Are you more or less worried about COVID-19 today than a few weeks ago? Tell us in the Comments Section and visit our Facebook page. 22_______________________________________________________________ 23Words in This Story 24pill - n. a small, rounded object that you swallow and that contains medicine, vitamins, etc. 25variant - n. something that is different in some way from others of the same kind 26symptom - n. a change in the body or mind which indicates that a disease is present 27insurance - n. an agreement in which a person makes regular payments to a company and the company promises to pay money if the person is injured or dies, or to pay money equal to the value of something (such as a house or car) if it is damaged, lost, or stolen